Search results for "zinc complex"

showing 4 items of 4 documents

Ditopic Aza-Scorpiand Ligands Interact Selectively with ds-RNA and Modulate the Interaction upon Formation of Zn2+ Complexes

2021

Nucleic acids are essential biomolecules in living systems and represent one of the main targets of chemists, biophysics, biologists, and nanotechnologists. New small molecules are continuously developed to target the duplex (ds) structure of DNA and, most recently, RNA to be used as therapeutics and/or biological tools. Stimuli-triggered systems can promote and hamper the interaction to biomolecules through external stimuli such as light and metal coordination. In this work, we report on the interaction with ds-DNA and ds-RNA of two aza-macrocycles able to coordinate Zn2+ metal ions and form binuclear complexes. The interaction of the aza-macrocycles and the Zn2+ metal complexes with duple…

Cell SurvivalMetal ions in aqueous solutionÀcids nucleicsPharmaceutical Science010402 general chemistryLigands01 natural sciencesArticleAnalytical ChemistryMetalchemistry.chemical_compoundQD241-441Coordination ComplexesCell Line TumorDrug DiscoveryChlorocebus aethiopsAnimalsHumansPhysical and Theoretical ChemistryVero CellsRNA Double-Strandedchemistry.chemical_classification010405 organic chemistryCytotoxinsBiomoleculeOrganic Chemistryzinc complexRNADNASmall moleculeFluorescenceCombinatorial chemistry0104 chemical sciencesZincchemistryChemistry (miscellaneous)visual_artDNA and RNA duplexesvisual_art.visual_art_mediumNucleic acidMolecular MedicineRNAaza-macrocycleDNAMolecules
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Heterometallic CoII-CoIII-MII alkoxido-bridged heptanuclear motifs (M = Cu, Zn). Syntheses, crystal structures and magnetic properties

2018

Two new alkoxido-bridged heterometallic complexes of formula [CoIICoIII 3CuII 3(dea)6(CH3COO)3](ClO4)0.75(CH3COO)1.25 (1) and [CoII 2CoIII 2ZnII 3(tea)2(piv)6(CH3O)2(OH)2(CH3OH)2]·H2O 2 (H2dea=diethanolamine, H3tea=triethanolamine and Hpiv=pivalic acid) have been assembled using aminoalcohol ligands. The cationic core in 1 possesses a threefold crystallographic axis, and it exhibits a set of three copper(II), one cobalt(II) and three cobalt(III) ions arranged as a hexagon of alternating copper(II) and cobalt(III) ions around the central cobalt(II) ion. Each edge of the hexagon is defined by a double alkoxido bridge, the outer one being bis-monodentate with copper(II)-cobalt(III) pair wherea…

Denticity/dk/atira/pure/subjectarea/asjc/2500/2505Inorganic chemistrychemistry.chemical_elementCrystal structureZinc010402 general chemistry01 natural sciencesCobalt complexesIonInorganic ChemistryMagnetic propertiesZinc complexesMaterials ChemistryPhysical and Theoretical Chemistry/dk/atira/pure/subjectarea/asjc/1600/1606/dk/atira/pure/subjectarea/asjc/1600/1604010405 organic chemistryLigandCopper0104 chemical sciencesCrystallographychemistryIntramolecular forceMixed-valence clustersCobaltCopper complexesInorganica Chimica Acta
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Extended dipyrrin ligands : candidates for optical metal ion detection under competitive conditions

2017

Acylhydrazone based extended dipyrrins L1-H and L2-H are introduced as complexometric ppb sensitive metal ion detectors. The binding of lanthanide, transition as well as post-transition metal ions is followed by UV-Vis measurements. The carbohydrate based ligand L2 is water soluble and thus can act as a metal ion sensor in this medium.

LanthanideMetal ions in aqueous solutionInorganic chemistrymetal ion detection010402 general chemistry01 natural sciencesCatalysisMetalMaterials Chemistryta116water solubility010405 organic chemistryLigandChemistryMetals and AlloysGeneral Chemistrydipyrrin ligands0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsIon sensorWater solublevisual_artCeramics and Compositesvisual_art.visual_art_mediumzinc complexesChemical Communications
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Catalytic Enantioselective Cyclopropylalkynylation of Aldimines Generated In Situ from α-Amido Sulfones

2022

A convenient procedure of synthesis of N-carbamoyl-protected propargylic amines substituted with a cyclopropyl group from α-amido sulfones and cyclopropylacetylene is described. The reaction is catalyzed by a chiral BINOL-type zinc complex and provides the corresponding products in good yields and enantioselectivities.

Organic ChemistryPharmaceutical ScienceStereoisomerismCatalysisAnalytical ChemistryZinc<i>N</i>-carbamoyl-protected propargylic amines; α-amido sulfones; cyclopropylacetylene; BINOL; zinc complexCatàlisiChemistry (miscellaneous)Drug DiscoveryMolecular MedicineSulfonesAminesPhysical and Theoretical ChemistryQuímica orgànica
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